The best Side of cees dekker
The best Side of cees dekker
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‘Sure, that is about proper. I try to find a Bodily knowledge of biological units inside a base-up way. I think you could distinguish 3 traces of study in my group in the meanwhile. The main fears chromosome framework: How does one obtain a metre-very long DNA polymer folded and organised in this kind of microscopic mobile? We've got designed visualisation procedures that permit us to study how, by way of example, SMC proteins loop DNA (online video on Youtube) to be able to Create up chromosomes.
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Deposition and atomic power microscopy of person phthalocyanine polymers in between nanofabricated electrodes
2010, created a fresh way (‘wedging transfer’) to control nanostructures; initially report of DNA translocation as a result of graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into strong-state nanopores
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
All parameters have been the exact same for every panel in this video, except for the Preliminary placement in the 6hb rod (demonstrated in blue) to the nanopore. Simulations that terminated early because of translocation on the rod through the pore are marked by a grey history.
Studying DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
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Bulk-floor coupling identifies the mechanistic connection in between Min-protein designs in vivo and in vitro
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Nature Physics many thanks the anonymous reviewers for his or her contribution for the peer review of the function.
For example, we think about the nucleopore intricate, a gateway in between the mobile nucleus plus the cytoplasm. This is an extremely complicated process and so hard to analyze in the cell, so we use biomimetics. We reconstruct holes after which you can insert specific components of your nucleopore intricate to study transportation via it at The one-molecule degree.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden cees dekker is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij fulfilled enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever style in 2005. (nl)